Proteomics instrumentation of our lab includes state-of-the-art Orbitrap Fusion Lumos Tribrid mass spectrometer coupled with Dionex UHPLC chromatography system which are in use for analysis of whole proteomes and protein interactomics. Purification of proteins and their complexes is facilitated by four AKTA FPLC systems. Analysis of protein samples homogeneity by dynamic light scattering is performed using DynaPro NanoStar machine.
NYU Langone Medical Center has a range of cryo–electron microscopes operated by expert staff. So far, one 300kV Thermo Scientific Titan Krios G3i and one 200kV Talos Arctica with Gatan K2 Summit direct detection camera have been installed in Cryo-Electron Microscopy Laboratory. We use these state-of-the-art cryo-electron microscopes to study near-atomic resolution structures of interested biomacromolecules.